To quote Keith:
“… it was a criticism about the sound synchronization in a Playstation emulator. I would have expected to find some buffering system implemented in the audio code, but instead it was only limited by how often the call to write(/dev/dsp) returned. That had the effect of delaying all your sound by the size of the kernel audio buffer.”
The origin of the quote was, as I dimly recall, a criticism of a playstation emulator's approach to audio playback scheduling.
The irony is that this phrase does not come from anyone within the Twisted community. It's a quote from Keith Zaback, who casts a very light footprint on the interwebs.
One of my favorite catch-phrases in the Twisted community is:
"Spawn a thread, write 'til you block!"
Given that one may frequently be interacting with async-hostile frameworks from within Twisted, this is usually an expression of exasperation; "oh well, I guess I'm going to do this dumb thing since I have no better options".